Reishi Mushroom botanical illustration

Functional Mushroom

Reishi Mushroom

Ganoderma lingzhi RAY-shee

Reishi is a glossy, woody fungus with a long history of use in East Asian botanical traditions.

Contemporary functional products generally use a prepared fungal extract rather than the tough whole fruiting body.

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CALM
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Ingredient profileReishi Mushroom
Scientific nameGanoderma lingzhi
OriginEast Asia
Part usedFruiting Body & Spores
ExtractionWater Extraction
Final formExtract
Associated withMIND, CALM

Ingredient guide

What is Reishi Mushroom?

Reishi is the common name used for fungi in the Ganoderma group, with Ganoderma lingzhi used in our ingredient record. The mushroom has a glossy, woody fruiting body and a long history of use in East Asian traditions. Because the mature mushroom is tough rather than culinary in texture, modern wellness products commonly use powders or extracts.

Reishi contains several groups of compounds that have attracted scientific interest, particularly beta-glucans and other polysaccharides, plus triterpenoids such as ganoderic acids. These constituents have been widely studied in laboratory and animal research. Human evidence is much less certain. A recent systematic review and meta-analysis of clinical trials found that some measured outcomes changed in particular analyses, but the certainty of evidence was rated very low and many commonly discussed cardiometabolic markers did not show significant effects.

That makes Reishi a good example of why an ingredient hub should separate traditional use, chemistry and human evidence. The existence of biologically active compounds does not automatically prove a consumer wellness claim.

At The London Dispensary, Reishi is used in our Balance fruit jellies alongside Ashwagandha and broad-spectrum CBD. The current product specification states that the Reishi is UK-grown and that the extract includes spores.

Source to formula

Botanical profile

OriginEast Asia
Part usedFruiting Body & Spores
ExtractionWater Extraction
Final formExtract

The Reishi used in our Balance fruit jellies is grown in the UK. The current product specification states that the Reishi extract includes spores.

Key compounds

Beta-glucans and polysaccharides

Complex fungal carbohydrates that are widely studied across Ganoderma species. Structure and extraction method can influence the resulting material.

Ganoderic acids and other triterpenoids

A family of Reishi triterpenes that contribute to the distinctive chemistry of Ganoderma species and are widely investigated in preclinical research.

Sterols and other fungal constituents

Reishi also contains sterols, nucleosides, proteins and other compounds; their concentrations vary by species, fungal material and extraction method.

Evidence, carefully read

What the science says

Reishi has an extensive preclinical literature, but the human clinical evidence is much less definitive than the ingredient’s long traditional history might suggest.

01

Polysaccharide research

Ganoderma beta-glucans and related polysaccharides are heavily studied for interactions with immune and gut-related pathways, especially in laboratory and preclinical models.

02

Triterpenoid chemistry

Ganoderic acids and related triterpenoids are another major research focus. Much of the mechanistic work remains preclinical rather than evidence for a consumer health outcome.

03

Clinical evidence remains low certainty

A 2025 meta-analysis of randomised trials found some modest changes in selected outcomes but rated the overall certainty of evidence as very low, with many commonly measured outcomes showing no significant effect.

View research references
  1. The Nutritional Significance of Ganoderma lucidum on Human Health: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical TrialsFood Science & Nutrition / PubMed, 2025
  2. Ganoderma lucidum (Reishi) – comprehensive and critical reviewPhytotherapy Research / PubMed, 2021
  3. Recent Advances in the Preparation, Structure, and Biological Activities of β-Glucan from Ganoderma SpeciesFoods / PubMed, 2023
  4. Review of the molecular mechanisms of Ganoderma lucidum triterpenoidsEuropean Journal of Medicinal Chemistry / PubMed, 2019

Inside our formulas

How we use Reishi Mushroom

Why we use it

Reishi is the functional-mushroom component of our Balance fruit jellies, giving the formula a clearly identified mushroom ingredient alongside its botanical and cannabinoid components.

The form we use

The current ingredient record lists water extraction and an extract final form. The current Balance product specification states that the Reishi extract includes spores.

Where we source it

The Reishi used in our Balance fruit jellies is UK-grown.

Why we pair it

In Balance fruit jellies we pair Reishi with Ashwagandha and broad-spectrum CBD in a single mixed-fruit formula.

From the dispensary

Products containing Reishi Mushroom

The botanical notebook

Read more about Reishi Mushroom

Good to know

Questions about Reishi Mushroom

What is Reishi mushroom?

Reishi is the common name for mushrooms in the Ganoderma group. Our ingredient record uses Ganoderma lingzhi.

What compounds are found in Reishi?

Reishi contains beta-glucans and other polysaccharides, triterpenoids such as ganoderic acids, sterols and additional fungal constituents.

Is Reishi evidence mainly clinical or preclinical?

A large amount of Reishi research is laboratory or animal-based. Human trials exist, but recent evidence reviews describe the certainty as low or very low for many outcomes.

What form of Reishi does TLD use?

The current Balance product uses UK-grown Reishi extract and the product specification states that spores are included.

Which products contain Reishi?

The product section on this hub should update automatically from the live product-to-ingredient relationship.